A Comprehensive Guide on the Significance of Coenzyme Q-10

Significance of Coenzyme Q-10Coenzyme Q10 (CoQ10) is a powerful substance akin to a vitamin, produced by the body naturally and through diet. This substance is rather crucial as it performs a major role in vital body functions.

CoenzymeQ10- Introduction

Present in most individuals, animals, bacteria and plants, Coenzyme Q10 promote certain unique reactions chemically in the body to defend free radical damage. Moreover, CoQ10 exists in the cells that make energy plays an effective role in creating the molecule ATP(adenosine5triphosphate) further performs a significant task of producing protein in the body. Apart from this it enhances circulation and immune health, encourages oxygen supply to the tissues and boasts of offering incredible anti-aging effects. Although this substance reduces with age, deficiencies of CoQ10 result in certain medical conditions, some of which are genetic.

CoQ10 in the Body

Active in large numbers of the eukaryotic cells, particularly in the mitochondria, CoQ10 an oil soluble compound, mimicking a vitamin, is present in each cell of the body. Nevertheless, these exist in enormous strengths in vital organs such as the brain, heart, liver and kidney.

Available Forms

CoQ10 Supplements are available in various forms. They are …

  • Tablets form
  • Hard shell capsules
  • Soft gel capsules
  • Oral spray

Dietary Sources

Most important dietary sources of CoQ10 include … CoQ10 in the Body


Oily varieties of fish such as salmon, Mackerel, sardines and tuna


Organ meats such as liver, beef, muscle and heart besides pork, beef and lamb


These include chicken and eggs


These include cruciferous vegetables namely Chinese cabbage, broccoli and cauliflower. Apart from this leafy greens like parsley and spinach.


Apple, avocado, grapefruit, orange, black currant and strawberry

Nuts & Seeds

Hazelnuts, almonds, pistachios, walnuts, Peanuts and sesame seeds

CoQ10 Uses and Benefits

free radicalsFree Radicals

Free radical elements build up in the tissues due to environmental toxins. This acts as a byproduct of the metabolic processes causing DNA damage, which often lead to premature ageing and other degenerative diseases such as cancer and heart disease. Nevertheless, antioxidant compounds in general scavenge these harmful free radical elements and helps thwart oxidative damage, thereby protecting the body from serious ailments.

Blood Pressure

Several studies point out the effectiveness of CoQ10 in lowering blood pressure levels in hypertensive patients after about four to twelve weeks. According to studies, CoQ10 has the ability to reduce systolic pressure by 17mm Hg and diastolic pressure by 10 mmHg. Nevertheless, it is imperative to avoid self-medication and seek the help of a physician.


The efficacy of CoQ10 on Diabetics is slightly contradictory. Nevertheless, certain studies prove that CoQ10 besides fighting oxidative stress also showed improved glycemic control.


The potent antioxidant substances in CoQ10 prevent formation of clots in the arterial walls by restricting blood coagulation. Hence, they prove effective against atherosclerosis, a harbinger of cardiovascular diseases.

CoQ10 Deficiency Cholesterol

CoQ10 deficiency has a tendency to increase blood cholesterols in the body. Hence, they remain one of the main treatment options for people suffering from elevated blood cholesterol levels. Moreover, this has the potential to reduce the side effects of standard prescription drug known as statins that have a tendency to reduce the natural levels of CoQ10 in the body.


Taking CoQ10 supplements within three days of an attack has the possibility to avert subsequent heart attacks and angina in the future. Moreover, CoQ10 supplements, taken along with prescription drugs helped ease symptoms such as accumulation of fluid in the legs and lungs, insomnia, exhaustion, increased exercise tolerance and shortness of breath. Further, CoQ10 administered before any major cardiac surgery helps strengthen the heart, alleviate fee radical damage and prevents occurrences of angina and arrhythmias during the recovery period.


One of the key factors for the formation of cancer (carcinogenesis) is the Reactive oxygen species (ROS) that instigate extensive damage to DNA. Studies reveal a correlation between CoQ10 deficiency and advanced stages of cancer .Therefore, apart from conventional treatment and prescription drugs, administering CoQ10 supplements in combination antioxidants such as omega3 and 6 fatty acids would especially help women suffering from advanced breast cancer.

Other Benefits

  • CoQ10 antioxidant elements promote immune health and therefore prove beneficial for those suffering from AIDS and HIV
  • This crucial substance present in cells that produce energy help create adenosine5triphosphate (ATP) an important molecule strengthens muscles and boosts energy.
  • CoQ10 helps strengthen the muscles and enhance athletic performance with better exercise tolerance in cases of genetically inherited muscular dystrophy.
  • This substance inhibits cognitive decline with a reduced risk of stroke, Alzheimer’s and Parkinson’s diseases.
  • CoQ10 accelerated tissue repair and healing in periodontal diseases, occurring due to low levels of this vital element in the body.
  • CoQ10 supplements taken from the 20th week of pregnancy reduce risk of preeclampsia
  • It augments sperms with improved mobility in men with infertility.
  • It provides antiaging effects and stops hair loss

CoQ10 Deficiency

The symptoms of CoQ10 deficiency occur gradually over a period and often these remain unnoticed. Some of the problems correlated with deficiencies are…

  • Cardiac problems such as mitral valve prolapse (MVP)
  • Cardiomyopathy
  • Breathlessness
  • Arrhythmias
  • Muscular weakness
  • Joint pain
  • Weight gain

Side Effects

Despite its effectiveness, CoQ10 in certain instances imparts side effects. Hence, it is advisable to exercise caution while taking supplements, after consulting a health care professional.
This substance is unsuitable for expectant mothers and children below 18 years of age. Moreover, there is a potential risk of this enzyme interfering with blood pressure levels prior or post surgical procedures. Hence, it is crucial to discontinue medication temporarily two weeks prior to any invasive procedure after seeking a professional’s help.

Other side effects include…

  • Low blood pressure
  • Low blood sugar
  • Low sperm count
  • Headache
  • Appetite loss
  • Heartburn
  • Diarrhoea
  • Nausea
  • Vomiting
  • Skin irritation
  • Rashes
  • Flulike symptoms

Drug Interactions

Certain prescription drugs interfere withCoQ10 supplements, they are…

  • Anticoagulants
  • Blood pressure medications
  • Cholesterol medications
  • Antidepressants